2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Drug Metabolite

Drug Metabolite

Drug Metabolite

Related Products

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Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W019773
    Albendazole sulfone
    Albendazole sulfone is a metabolite of Albendazole, and exhibits anti-parasite effect against Echinococcus multilocularis Metacestodes.
    Albendazole sulfone
  • HY-100046R
    Nordoxepin (hydrochloride) (Standard)
    Nordoxepin (hydrochloride) (Standard) is the analytical standard of Nordoxepin (hydrochloride). This product is intended for research and analytical applications. Nordoxepin hydrochloride is the major metabolite of Doxepin. Doxepin is a tricyclic antidepressant that is widely prescribed for the research of mild depression.
    Nordoxepin (hydrochloride) (Standard)
  • HY-110034R
    Didesmethylsibutramine (hydrochloride) (Standard)
    Didesmethylsibutramine (hydrochloride) (Standard) is the analytical standard of Didesmethylsibutramine (hydrochloride). This product is intended for research and analytical applications. Didesmethylsibutramine (BTS 54-505) hydrochloride is the primary amine metabolite of Sibutramine (antidepressant and anti-obesity agent). Didesmethylsibutramine hydrochloride inhibits NMDA-evoked activity. Didesmethylsibutramine hydrochloride is also a reuptake inhibitor. Didesmethylsibutramine hydrochloride induces thermogenesis.
    Didesmethylsibutramine (hydrochloride) (Standard)
  • HY-100651R
    Desmethylnortriptyline (Standard)
    3,5-Di-tert-butyl-4-hydroxybenzaldehyde (Standard) is the analytical standard of 3,5-Di-tert-butyl-4-hydroxybenzaldehyde. This product is intended for research and analytical applications. 3,5-Di-tert-butyl-4-hydroxybenzaldehyde (BHT-CHO) is a metabolite of Butylated hydroxytoluene (HY-Y0172) .
    Desmethylnortriptyline (Standard)
  • HY-W144308
    Tetrachlorohydroquinone
    		98.45%
    Tetrachlorohydroquinone (TCHQ) is a metabolite of pentachlorophenol. Tetrachlorohydroquinone increases DNA lesions and induce oxidative stress in rodents.
    Tetrachlorohydroquinone
  • HY-W004298R
    10-Undecen-1-ol (Standard)
    10-Undecen-1-ol (Standard)
  • HY-121456
    Salnacedin
    Salnacedin (G-201) has anti-inflammatory and keratolytic activity. Salnacedin can be used in the research of seborrhoeic dermatitis and acne.
    Salnacedin
  • HY-100644
    Trimethoprim N-oxide
    Trimethoprim N-oxide (Trimethoprim 1-N-oxide) belongs to human urinary metabolites. Trimethoprim N-oxide is generated by oxidation of nitrogen atoms in the pyrimidine ring. Trimethoprim N-oxide is formed predominantly by CYP1A2 in human liver microsomes.
    Trimethoprim N-oxide
  • HY-18719ER
    Endoxifen (Standard)
    Methicillin (sodium hydrate) (Standard) is the analytical standard of Methicillin (sodium hydrate). This product is intended for research and analytical applications. Methicillin sodium hydrate is a narrow-spectrum β-lactam antibiotic, acts by inhibiting penicillin-binding proteins (PBPs). Methicillin sodium hydrate is active against Staphylococcus aureus and Staphylococcus epidermidis that are resistant to other penicillins. Methicillin sodium hydrate can be used for the research of skin infections, osteomyelitis, and endocarditis.
    Endoxifen (Standard)
  • HY-139267
    (±)19(20)-EpDTE
    (±)19(20)-EpDTE is an oxylipin and an oxidative metabolite of docosapentaenoic acid.
    (±)19(20)-EpDTE
  • HY-108229
    6β-Naltrexol
    6β-Naltrexol (6β-Hydroxynaltrexone), the primary metabolite of Naltrexone, is a peripherally selective opioid antagonist. 6β-Naltrexol selectively inhibits gastrointestinal opioid effects in human subjects and inhibits Morphine-induced slowing of gastrointestinal transit.
    6β-Naltrexol
  • HY-W009934R
    2-Phenyl-2-(2-pyridyl)acetonitrile (Standard)
    2-Phenyl-2-(2-pyridyl)acetonitrile (Standard)
  • HY-I0678S1
    Regorafénib N-oxyde (M2)-13C,d3
    Regorafénib N-oxyde (M2)-13C,d3 is the 13C- and deuterium labeled Regorafénib N-oxyde (M2). Regorafénib N-oxyde M2 is an active metabolite of Regorafenib. Regorafenib is a multi-target inhibitor for VEGFR1/Flt-1/2/3, PDGFRβ, Kit, RET and Raf-1 with IC50s of 13/4.2/46, 22, 7, 1.5 and 2.5 nM, respectively.
    Regorafénib N-oxyde (M2)-<sup>13</sup>C,d<sub>3</sub>
  • HY-123006
    Aszonalenin
    Aszonalenin is a metabolite of Aspergillus zonatus.
    Aszonalenin
  • HY-W778830
    Bodipy C12-ceramide
    Bodipy C12-ceramide (B12Cer) is a fluorescently tagged form of C12-Ceramide (HY-100353) that displays excitation/emission maxima of 505/540 nm, respectively. Bodipy C12-ceramide is formed when acid sphingomyelinase hydrolyzes BODIPY-C12 sphingomyelin in vitro and has been used to quantify acid sphingomyelinase activity in plasma with Niemann-Pick disease.
    Bodipy C12-ceramide
  • HY-137208
    Chondroitin disaccharide Δdi-0S sodium
    Chondroitin disaccharide Δdi-0S sodium is an unsaturated disaccharide produced by the degradation of Chondroitin sulfate (HY-B2162). Chondroitin disaccharide Δdi-0S sodium produces fluorescent pyridylamino derivative with 2-aminopyridine, which can be used in studies about the metabolic pathway of Chondroitin sulfate and related disease mechanisms.
    Chondroitin disaccharide Δdi-0S sodium
  • HY-118517
    α-Hydroxytamoxifen
    α-Hydroxytamoxifen is a metabolite of tamoxifen, reacts with DNA in the absence of metabolizing enzymes, and causes formation of DNA adducts.
    α-Hydroxytamoxifen
  • HY-125947R
    4-Epioxytetracycline (Standard)
    4-Epioxytetracycline (Standard) is the analytical standard of 4-Epioxytetracycline. This product is intended for research and analytical applications. 4-Epioxytetracycline, the degradation product of Oxytetracycline (OTC), can be found in swine manure compost and wastewater.
    4-Epioxytetracycline (Standard)
  • HY-N12842
    2-Deoxokanshone L
    2-Deoxokanshone L is a degradation product of Nardosinone (HY-N0380).
    2-Deoxokanshone L
  • HY-137591
    13,14-Dihydro-15-keto-PGE1
    13,14-Dihydro-15-keto-PGE1 is an inactive metabolite of PGE1. 13, 14-Dihydro-15-Keto-pGE1 inhibited platelet aggregation in ADP-induced human isolated platelet-rich plasma with IC50 14.8 μg/mL.
    13,14-Dihydro-15-keto-PGE1
Cat. No. Product Name / Synonyms Application Reactivity